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what to have .net framework 4.0 client for profile or .net framework 4.0

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Hi,

I am working on outlook addin project being developed in vs2010 for outlook 2007. the addin project is being developed in vb.net and there is one another project in the main project which is devloped in c#

the c# project is basically for calling some internal web services, which interacts with database and returns a json response. i need to know,  which is the best choice in between .net framework 4.0 client profile or .net framework 4.0 to handle the web services part

Thanks

 


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